Respiratory System

Nose, Steno's Glands - Degeneration

    Narrative
    Nose, Steno's glands - Normal in a male F344/N rat from a chronic study. Normal Steno's glands are shown for comparison with Figures 2-4., basic_html
    Nose, Steno's glands - Atrophy in a male F344/N rat from a chronic study. There is generalized loss of glandular acini in the Steno's glands., basic_html
    Nose, Steno's glands - Atrophy in a male B6C3F1/N mouse from a subchronic study. Focal atrophy is characterized by a localized loss of glandular acini (arrow)., basic_html
    Nose, Steno's glands - Atrophy in a male B6C3F1/N mouse from a subchronic study (higher magnification Figure 3). There is loss of cells in the Steno's Gland acini, with morphology suggestive of apoptosis., basic_html

    Authors

    Rodney A. Miller, DVM, PhD, DACVP
    NC Pathology Group Manager
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Reviewers

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Ronald Herbert, DVM, PhD
    NTP Pathologist
    Group Leader, Pathology Support Group
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC