Nose, Turbinate - Atrophy

Nose, Turbinate - Normal in a male B6C3F1/N mouse from a subchronic study. Normal turbinates at level I are shown for comparison with Figure 2.
Figure 1 of 4

Nose, Turbinate - Atrophy in a male B6C3F1/N mouse from a subchronic study. The size of the turbinates is decreased compared with normal turbinates shown in Figure 1.
Figure 2 of 4

Nose, Turbinate - Normal in a male B6C3F1/N mouse from a subchronic study. Normal turbinates at level III are shown for comparison with Figure 4.
Figure 3 of 4
comment:
Atrophy of the turbinats ( Figure 2



recommendation:
Atrophy of the turbinates should be diagnosed whenever present and assigned a severity grade. Other lesions, including perforation of the nasal septum and hyperostosis, should be diagnosed separately when warranted by their prominence or severity.related links:
Nose, Olfactory Epithelium – Atrophyreferences:
Boorman GA, Morgan KT, Uraih LC. 1990. Nose, larynx, and trachea. In: Pathology of the Fischer Rat: Reference and Atlas (Boorman GA, Eustis SL, Elwell MR, eds). Academic Press, San Diego, 315-337.
Harkema JR, Catalano PJ, Hotchkiss JA. 1997. Consequences of Prolonged Inhalation of Ozone on F344/N Rats: Collaborative Studies. Part XII: Atrophy of Bone in Nasal Turbinates. Research Report No. 65. Health Effects Institute, Cambridge, MA. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/9140147
Monticello TM, Morgan KT, Uraih LC. 1990. Nonneoplastic nasal lesions in rats and mice. Environ Health Perspect 85:249-274. Full Text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568333/
Web page last updated on: February 23, 2015