Nose, Turbinate - Hyperostosis



comment:
Hyperostosis is an increase in the amount of bone resulting in a thickened anatomic structure ( Figure 1





recommendation:
Hyperostosis should be diagnosed whenever present and assigned a severity grade. All accompanying lesions, such as inflammation, turbinate atrophy, and olfactory epithelial atrophy, should be diagnosed separately.references:
Boorman GA, Morgan KT, Uraih LC. 1990. Nose, larynx, and trachea. In: Pathology of the Fischer Rat: Reference and Atlas (Boorman GA, Eustis SL, Elwell MR, eds). Academic Press, San Diego, 315-337.
Monticello TM, Morgan KT, Uraih LC. 1990. Nonneoplastic nasal lesions in rats and mice. Environ Health Perspect 85:249-274. Full Text: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568333/
National Toxicology Program. 1982. NTP TR-228. Carcinogenesis Bioassay of Vinylidene Chloride (CAS No. 75-35-4) in F344 Rats and B6C3F1 Mice (Gavage Study). NTP, Research Triangle Park, NC. Abstract: http://ntp.niehs.nih.gov/go/7064
National Toxicology Program. 2011. NTP TR-566. Toxicology and Carcinogenesis Studies of Diethylamine (CAS No. 109-89-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). NTP, Research Triangle Park, NC. Abstract: http://ntp.niehs.nih.gov/go/34820
Web page last updated on: February 23, 2015