Special Senses System

Ear - Inflammation

    Narrative
    Ear - Inflammation, Acute in a male Fischer 344/N rat from a chronic study. There is predominantly neutrophilic infiltrates in the epithelium and lamina propria and abundant neutrophils and proteinaceous fluid in the external ear canal (arrow).
    Ear - Inflammation, Chronic active in a male Fischer 344/N rat from a chronic study. There are neutrophils and mononuclear cells in the lamina propria (arrow) extending into the hyperplastic epithelium (arrowhead) lining the tympanic cavity.
    Ear - Inflammation, Suppurative in a male F344/N rat from a chronic study. There is intraluminal necrotic debris and neutrophils (arrow); epithelial necrosis with denudation and neutrophil infiltration of the laminal propria is also present.
    Ear - Inflammation, Chronic in a female Fischer/344N rat from a chronic study. There are macrophages and mononuclear cells in
    Ear - inflammation, chronic in a female Fischer/344N rat from a chronic study (higher magnification of Figure 4). The inflammatory cells and fibrosis in the wall of the external ear canal are shown in greater detail.

    Author

    Margarita M. Gruebbel, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Ruth E. Hurley, DVM, PHD, DACVP
    Senior Veterinary Pathologist
    Huntingdon Life Sciences
    North Brunswick, NJ

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC