Eye, Conjunctiva - Edema
comment:Edema of the bulbar conjunctiva ( Figure 1 , Figure 2 , and Figure 3 ) is characterized by diffuse swelling due to accumulation of clear to pale eosinophilic fluid. Clinically, conjunctival edema is referred to as chemosis. It is a nonspecific finding secondary to such causes as topical irritants, allergens, trauma, and infectious agents. Inflammatory cells may be present in the edematous areas.
recommendation:Conjunctival edema should be diagnosed and assigned a severity grade. If located in the bulbar conjunctiva, edema can be diagnosed under the organ/subtopography "eye, conjunctiva." If located in the palpebral conjunctiva, it can be diagnosed under the organ/subtopography of “skin, eyelid.” If secondary to another process (e.g., inflammation), conjunctival edema should not be diagnosed separately (unless warranted by severity) but should be described in the narrative.
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Maurer JK, Parker RD, Carr GJ. 1998. Ocular irritation: Microscopic changes occurring over time in the rat with surfactants of known irritancy. Toxicol Pathol 26:217-225. Abstract: http://tpx.sagepub.com/content/26/2/217.short
National Toxicology Program. 1994. NTP TR-437. Toxicology and Carcinogenesis Studies of Hexachlorocyclopentadiene (CAS No. 77-47-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). NTP, Research Triangle Park, NC. Abstract: http://ntp.niehs.nih.gov/go/6018
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