Special Senses System

Eye, Cornea - Hyperplasia, Squamous

    Narrative
    Eye, Cornea - Hyperplasia, Squamous in a male B6C3F1 mouse from a chronic study. There are increased cell layers of the corneal epithelium (arrow) and superficial hyperkeratosis (arrowhead) with inflammation in the underlying stroma (asterisk).
    Eye, Cornea - Hyperplasia, Squamous in a male B6C3F1 mouse from a chronic study (higher magnification of Figure 1). The corneal squamous epithelium is thickened (arrow) by increased layers of cells and hyperkeratosis (arrowhead).
    Eye, Cornea - Hyperplasia, Squamous in a male F344/N rat from a chronic study. There are increased numbers of cell layers with exophytic and endophytic
    Eye, Cornea - Hyperplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 3). This higher magnification image shows the marked hyperplasia in greater detail.

    Author

    Margarita M. Gruebbel, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Ruth E. Hurley, DVM, PHD, DACVP
    Senior Veterinary Pathologist
    Huntingdon Life Sciences
    North Brunswick, NJ

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC