Eye, Cornea - Metaplasia, Goblet Cell
comment:Goblet cells are normally present in the conjunctival epithelium, but when they appear in the corneal epithelium, it is recognized as a metaplasitic change ( Figure 1 and Figure 2 ). Such so-called conjunctivalization of the corneal epithelium is considered a secondary reactive change, often associated with corneal neovascularization and/or inflammation from various causes.
recommendation:Corneal goblet cell metaplasia should be diagnosed and assigned a severity grade whenever present. It is generally reactive and secondary to other pathologic processes, but it’s unusual nature necessitates its diagnosis. When present, inflammation should be diagnosed separately.
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