Special Senses System

Eye, Cornea - Vacuolation, Cytoplasmic

    Narrative
    Eye, Cornea - Vacuolation, Cytoplasmic in a male F344/N rat from a chronic study. There are clear discrete vacuoles (arrow) in the corneal epithelial cells and inflammatory cells in the anterior chamber (A).
    Eye, Cornea - Vacuolation, Cytoplasmic in a male F344/N rat from a chronic study (higher magnification of Figure 1). There are clear discrete vacuoles in the superficial epithelial cells (arrow).
    Eye, Cornea - Vacuolation, Cytoplasmic in a male B6C3F1 mouse from a chronic study. There are clear vacuolesis present in the basal epithelial cells (arrow); there is also corneal epithelial hyperplasia (P) and hyperkeratosis (K).

    Author

    Margarita M. Gruebbel, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Ruth E. Hurley, DVM, PHD, DACVP
    Senior Veterinary Pathologist
    Huntingdon Life Sciences
    North Brunswick, NJ

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC