Urinary System

Kidney - Crystals

    Narrative
    Kidney, Renal tubule - Crystals in a male B6C3F1 mouse from a chronic study. There are crystals (arrows) within tubule lumens.
    Kidney, Renal tubule - Crystals in a male rat from an acute study. Crystal deposition with secondary inflammation is present in the renal papilla.
    Kidney, Renal tubule - Crystals in a female F344/N rat from a chronic study. A pigmented crystal is surrounded by multinucleated giant cells.

    Authors 

    John Curtis Seely, DVM, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Kendall S. Frazier, DVM, PhD, DACVP, DABT
    Director, Cellular and Molecular Pathology, Safety Assessment
    GlaxoSmithKline
    King of Prussia, PA

    Gordon C. Hard, BSc, BVSc, PhD, DSc, FRCPath, FRCVS, FAToxSci, DACVP
    Expert Consultant
    Tairua, New Zealand

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC