Kidney, Glomerulus - Metaplasia
comment:In the mouse, sexual dimorphism of the glomerular parietal epithelium of Bowman’s capsule exists. The female parietal epithelial cells are typically flattened ( Figure 1 ) and the male parietalepithelium can be both cuboidal and flattened. In glomerular metaplasia, caused by administration of some androgenic compounds, the female parietal epithelium becomes cuboidal, or male-like ( Figure 2 ).
recommendation:Glomerular metaplasia of Bowman’s capsule should be diagnosed and given a severity grade.
related links:Kidney, Renal Tubule - Hypertrophy
Seely JC. 1999. Kidney. In: Pathology of the Mouse: Reference and Atlas (Maronpot RR, Boorman GA, Gaul BW, eds). Cache River Press, Vienna, IL, 207-234. Abstract: http://www.cacheriverpress.com/books/pathmouse.htm
Web page last updated on: October 28, 2014