Urinary System

Kidney - Glomerulonephritis

    Narrative
    Kidney - Glomerulonephritis in a female B6C3F1 mouse from a chronic study. Glomerulonephritis is characterized by enlarged glomeruli with increased cellularity and mesangial expansion.
    Kidney - Glomerulonephritis in a female B6C3F1 mouse from a chronic study (higher magnification of Figure 1). Higher magnification of glomerulonephritis in a glomerulus.
    Kidney - Glomerulonephritis in a female B6C3F1 mouse from a chronic study (higher magnification of Figure 1). Higher magnification of the mesangial expansion and increased cellularity.
    Kidney - Normal glomerulus from a female B6C3F1 mouse from a subchronic study. Compare to Figures 1-3 (magnification may not be the same as that in Figures 1-3).

    Authors 

    John Curtis Seely, DVM, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Kendall S. Frazier, DVM, PhD, DACVP, DABT
    Director, Cellular and Molecular Pathology, Safety Assessment
    GlaxoSmithKline
    King of Prussia, PA

    Gordon C. Hard, BSc, BVSc, PhD, DSc, FRCPath, FRCVS, FAToxSci, DACVP
    Expert Consultant
    Tairua, New Zealand

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC