Urinary System

Kidney - Inflammation

    Narrative
    Kidney, Renal tubule - Inflammation, Acute in a male F344/N rat from a chronic study. Acute inflammatory cells are present in the renal tubule.
    Kidney, Renal tubule - Inflammation, Acute in a female F344/N rat from a chronic study. Acute tubule inflammatory cells associated with extension from renal pelvis inflammation are present.
    Kidney, Renal Pelvis - Inflammation, Chronic in a female F344/N rat from a chronic study. Inflammation involves the renal pelvis with infiltrates of inflammatory cells in the pelvis and peripelvic tissue; note the hyperplasia of the papillary epithelium and urothelium.
    Kidney, Renal Pelvis - Inflammation, Acute in a male F344/N rat from a chronic study. Acute inflammation is present within the renal pelvis and along the renal papilla.
    Kidney, Renal Pelvis - Inflammation, Suppurative in a male B6C3F1 mouse in a chronic study. Microabscesses may result from extension of renal pelvic inflammation into the renal medulla and cortex.
    Kidney, Renal Pelvis - Inflammation, Acute in a female F344/N rat from a chronic study. Necrosis of the renal papilla may result from marked inflammation of the renal pelvis.
    Kidney, Interstitium - Inflammation, Acute in a male F344/N rat from a chronic study. An acute interstitial inflammatory cell infiltrate and hemorrhage are present adjacent to the renal pelvis.
    Kidney, Interstitium - Inflammation, Chronic in a female F344/N rat from a chronic study. An area of chronic interstitial inflammation is characterized by mononuclear inflammatory cell infiltrates and fibrosis.

    Authors 

    John Curtis Seely, DVM, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Kendall S. Frazier, DVM, PhD, DACVP, DABT
    Director, Cellular and Molecular Pathology, Safety Assessment
    GlaxoSmithKline
    King of Prussia, PA

    Gordon C. Hard, BSc, BVSc, PhD, DSc, FRCPath, FRCVS, FAToxSci, DACVP
    Expert Consultant
    Tairua, New Zealand

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC