Urinary System

Kidney - Mineralization

    Narrative
    Kidney - Mineralization in a male F344 rat from an acute study. Spontaneous mineralization of cortical tubules is present.
    Kidney - Mineralization in a female Sprague-Dawley rat from an acute study. Mineralization is commonly observed in the area of the outer stripe and inner stripe of the outer medulla.
    Kidney - Mineralization in a male F344/N rat from a chronic study. Linear mineralization of papillary tubules is associated with alpha-2u-globulin nephropathy.

    Authors 

    John Curtis Seely, DVM, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Kendall S. Frazier, DVM, PhD, DACVP, DABT
    Director, Cellular and Molecular Pathology, Safety Assessment
    GlaxoSmithKline
    King of Prussia, PA

    Gordon C. Hard, BSc, BVSc, PhD, DSc, FRCPath, FRCVS, FAToxSci, DACVP
    Expert Consultant
    Tairua, New Zealand

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC