Urinary System

Kidney, Renal Tubule - Vacuolation, Cytoplasmic

    Narrative
    Kidney, Renal tubule - Vacuolation, Cytoplasmic in a treated male B6C3F1 mouse from a chronic study. Numerous clear vacuoles are present in the cytoplasm of renal tubule epithelial cells.
    Kidney, Renal tubule - Vacuolation, Cytoplasmic in a treated male B6C3F1 mouse from a chronic study (higher magnification of Figure 1). There are variably sized, mostly large vacuoles in the renal tubule epithelial cells.

    Authors 

    John Curtis Seely, DVM, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Kendall S. Frazier, DVM, PhD, DACVP, DABT
    Director, Cellular and Molecular Pathology, Safety Assessment
    GlaxoSmithKline
    King of Prussia, PA

    Gordon C. Hard, BSc, BVSc, PhD, DSc, FRCPath, FRCVS, FAToxSci, DACVP
    Expert Consultant
    Tairua, New Zealand

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC