Endocrine System

Adrenal Gland - Inflammation

    Narrative
    Adrenal gland, Cortex - Inflammation, Acute in a female B6C3F1/N mouse from a chronic study. There is infiltration by neutrophils (arrow) in the zona fasciculata with associated cortical cell degeneration and necrosis.
    Adrenal gland, Cortex - Inflammation, Acute in a female B6C3F1/N mouse from a chronic study. There is infiltration by neutrophils (arrow) in the zona fasciculata with associated cortical cell degeneration and necrosis.
    Adrenal gland, Cortex  Inflammation, Acute in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). There are neutrophils (arrow) in the sinusoids of the zona fasciculata with associated degeneration and necrosis of the cortical cells.
    Adrenal gland, Cortex Inflammation, Acute in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). There are neutrophils (arrow) in the sinusoids of the zona fasciculata with associated degeneration and necrosis of the cortical cells.

    Authors

    Mark J. Hoenerhoff, DVM, PhD, DACVP
    Associate Professor
    Veterinary Pathologist, In Vivo Animal Core
    Unit for Laboratory Animal Medicine
    University of Michigan
    Ann Arbor, MI

    Georgette D. Hill, D.V.M., Ph.D.
    Toxicologic Pathologist/Assistant Pathology Program Manager
    Comparative Molecular Pathology Division
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC

    Margarita M. Gruebbel, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Thomas J. Rosol, DVM, PhD, DACVP
    Professor of Veterinary Biosciences
    Senior Advisor, Life Sciences, Technology Commercialization and Knowledge Transfer
    The Ohio State University
    Columbus, OH

    Gordon Flake, MD
    Staff Scientist
    NTP Pathologist
    Cellular and Molecular Pathology Branch
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC