Alimentary System

Stomach, Forestomach, Epithelium - Degeneration

    Narrative
    Stomach, Forestomach, Epithelium - Degeneration in a female F344/N rat from a subchronic study. There is vacuolation along the basement membrane and below the keratin layer.
    Stomach, Forestomach, Epithelium - Degeneration in a female F344/N rat from a subchronic study (higher magnification of Figure 1).
    Stomach, Forestomach, Epithelium - Degeneration in a male B6C3F1 mouse from a chronic study. Degeneration characterized by vacuolated cells (arrow) is present.

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC