Tooth, Dentin - Basophilic Granules

Tooth, Dentin - Basophilic granules in a male F344/N rat from a chronic study. There are numerous, small basophilic granules within the dentin.
Figure 1 of 2
comment:
Basophilic granules in the dentin ( Figure 1

recommendation:
Basophilic granules should be diagnosed and graded whenever present.references:
Lindemann G, Nylen MU. 1979. Calcium fluoride containing granules produced in vitro in rat bones. Scand J Dent Res 87:381-389. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/295141
National Toxicology Program. 1996. NTP TR-393. Toxicology and Carcinogenesis Studies of Sodium Fluoride (CAS No. 7681-49-4) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies). NTP, Research Triangle Park, NC. Abstract: https://ntp.niehs.nih.gov/go/12237
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