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  • Pancreatic Islets - Cyst

    Image of cyst in the pancreatic islet from a male B6C3F1 mouse in a chronic study
    Pancreatic islet - cyst. The central portion of this islet is markedly dilated and is considered a cyst that contains some erythrocytes in a male B6C3F1 mouse from a chronic study.
    Figure 1 of 3
    Image of cyst in the pancreatic islet from a male B6C3F1 mouse in a chronic study
    Pancreatic islet - cyst. High magnification of the cystic islet in Figure 1 in a male B6C3F1 mouse from a chronic study.
    Figure 2 of 3
    Image of cyst in the pancreatic islet from a male B6C3F1 mouse in a chronic study
    Pancreatic islet - cyst. A cyst with an irregular contour is present in this islet in a male B6C3F1 mouse from a chronic study.
    Figure 3 of 3
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    comment:

    A cyst present in only one islet in a section of pancreas is distinguished from angiectasis based on its large size, lack of an endothelial lining, and the absence of dilation of other vascular spaces ( Figure 1image opens in a pop-up window  and Figure 2image opens in a pop-up window ).

    recommendation:

    Islet cysts are uncommon but should be documented when present. A severity grade is not required.

    references: