Parathyroid Gland - Fibrosis

Parathyroid Gland - Fibrosis in a female F344/N rat from a chronic study. Extensive fibrosis has replaced the parathyroid parenchyma and extended into the thyroid.
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comment:
Parathyroid fibrosis is characterized by fibrillar, eosinophilic material that expands the interstitium of the parathryorid gland and, when severe, replaces the parenchyma. It is a rarely seen change. There may be extension into the adjacent thyroid parenchyma. The significance of this lesion is uncertain.recommendation:
Rare lesions such as this should be diagnosed and given a severity grade.references:
Web page last updated on: August 11, 2014