Reproductive System, Female

Ovary - Inflammation

    Narrative
    Ovary - Inflammation, Suppurative in a female B6C3F1/N mouse from a chronic study. Large focal accumulations of intact and degenerating neutrophils are present in the ovary.
    Ovary - Inflammation, Suppurative in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). There is an accumulation of intact and degenerating neutrophils and macrophages in the ovarian parenchyma.
    Ovary - Inflammation, Suppurative in a female Swiss CD-1 mouse from a chronic study. A large aggregation of intact and degenerating neutrophils effaces much of the ovary.
    Ovary - Inflammation, Suppurative in a female Swiss CD-1 mouse from a chronic study (higher magnification of Figure 3). An aggregation of intact and degenerating neutrophils replaces the ovarian parenchyma.
    Ovary - Inflammation, Suppurative in a female Swiss CD-1 mouse from a chronic study (higher magnification of Figure 4). An aggregation of intact and degenerating neutrophils with adjacent fibrous tissue and mixed mononuclear cell infiltration effaces the ovarian parenchyma.
    Ovary - Inflammation, Chronic in a female B6C3F1/N mouse from a chronic study. There is a predominantly lymphocytic infiltration of the ovarian parenchyma.
    Ovary - Inflammation, Chronic in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 6). There is a predominantly lymphocytic infiltration of the ovarian parenchyma.
    Ovary - Inflammation, Chronic active in a female Harlan Sprague-Dawley rat from a chronic study. There is an infiltration of neutrophils and mononuclear cells.
    Ovary - Inflammation, Chronic active in a female Harlan Sprague-Dawley rat from a chronic study (higher magnification of Figure 8). An infiltration of neutrophils and mononuclear cells replaces the ovarian parenchyma.
    Ovary - Inflammation, Granulomatous in a female F344/N rat from a chronic study. Foci of macrophage aggregates are present in the ovary, with an associated mixed inflammatory cell infiltration.
    Ovary - Inflammation, Granulomatous in a female F344/N rat from a chronic study (higher magnification of Figure 10). There are prominent macrophage aggregates with an associated mixed inflammatory cell infiltration.

    Authors

    Gabrielle Willson, BVMS, Dip RC Path, FRC Path, MRCVS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Karen Y. Cimon, DVM, MS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Karen S. Regan, DVM, DABT, DACVP
    Pathologist
    Regan Path/Tox Services, Inc.
    Ashland, OH  

    Darlene Dixon, DVM, PhD, DACVP, Fellow, IATP
    Group Leader, Molecular Pathogenesis Group
    National Toxicology Program Laboratory
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC