Reproductive System, Female

Vagina - Inflammation

    Narrative
    Vagina - Inflammation, Acute in a female F344/N rat from a chronic study. The lumen of the vagina is filled with copious eosinophilic material.
    Vagina - Inflammation, Acute in a female F344/N rat from a chronic study. The lumen of the vagina is filled with copious eosinophilic material and neutrophils, and there is mucification of the vaginal epithelium.
    Vagina - Inflammation, Suppurative in a female F344/N rat from a chronic study. An area of suppurative inflammation is present in the vaginal wall.
    Vagina - Inflammation, Suppurative in a female F344/N rat from a chronic study (higher magnification of Figure 3). There is a lack of epithelial lining demarcating the inflammatory cells from the adjacent vagina.
    Vagina - Inflammation, Chronic active in a female B6C3F1/N mouse from a chronic study. Chronic active inflammation is present in a focal area of epithelial erosion.
    Vagina - Inflammation, Chronic active in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). A focal area of inflammation is associated with erosion of epithelium.

    Authors

    Gabrielle Willson, BVMS, Dip RC Path, FRC Path, MRCVS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Karen Y. Cimon, DVM, MS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Karen S. Regan, DVM, DABT, DACVP
    Pathologist
    Regan Path/Tox Services, Inc.
    Ashland, OH  

    Darlene Dixon, DVM, PhD, DACVP, Fellow, IATP
    Group Leader, Molecular Pathogenesis Group
    National Toxicology Program Laboratory
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC