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Spleen - Fibrosis - Gallery

Image of fibrosis in the spleen from a male F344/N rat in a chronic study
Spleen, Parenchyma - Fibrosis in a male F344/N rat from a chronic study. The splenic red pulp is contracted by fibrous connective tissue (arrow).
Image of fibrosis in the spleen from a male F344/N rat in a chronic study
Spleen, Parenchyma - Fibrosis in a male F344/N rat from a chronic study (higher magnification of Figure 1). The splenic white pulp is atrophied (arrow), and there is pigment within the surrounding fibrous connective tissue.
Image of fibrosis in the spleen from a male F344/N rat in a chronic study
Spleen, Capsule - Fibrosis in a male F344/N rat from a chronic study. The splenic capsule is expanded by fibrous connective tissue (arrow).
Image of fibrosis in the spleen from a male F344/N rat in a chronic study
Spleen, Capsule - Fibrosis in a male F344/N rat from a chronic study (higher magnification of Figure 3). The fibrotic splenic capsule is lined by hypertrophied mesothelial cells (arrow).