Spleen - Fibrosis - Gallery

Spleen, Parenchyma - Fibrosis in a male F344/N rat from a chronic study. The splenic red pulp is contracted by fibrous connective tissue (arrow).

Spleen, Parenchyma - Fibrosis in a male F344/N rat from a chronic study (higher magnification of Figure 1). The splenic white pulp is atrophied (arrow), and there is pigment within the surrounding fibrous connective tissue.