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    Image of atrophy (normal comparison) in the skin from a female F344/N rat in an acute study
    Normal skin in a control female F344/N rat from a 14-day repeated-dose study.
    Image of atrophy in the skin adnexa from a male B6C3F1 mouse in a chronic study
    Adnexal atrophy-smaller and reduced numbers of pilosebaceous units (arrows) in a male B6C3F1 mouse from a chronic study.
    Image of atrophy in the skin adnexa from a male B6C3F1 mouse in a chronic study
    Adnexal atrophy-smaller and reduced numbers of pilosebaceous units (arrows) in a male B6C3F1 mouse from a chronic study.
    Image of atrophy in the skin adnexa from a male B6C3F1 mouse in a chronic study
    Adnexal atrophy-severe adnexal atrophy in which adnexa are absent in a male B6C3F1 mouse from a chronic study.