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  • Penis, Epithelium - Hyperplasia

    Image of epithelial hyperplasia in the penis from a male B6C3F1 mouse in a chronic study
    Penis, Epithelium - Hyperplasia. Arrow indicates papillary proliferation of squamous epithelium in a male B6C3F1 mouse from a chronic study.
    Figure 1 of 2
    Image of epithelial hyperplasia in the penis from a male B6C3F1 mouse in a chronic study
    Penis, Epithelium - Hyperplasia. Higher magnification of Figure 1 showing the hyperplastic squamous epithelium in a male B6C3F1 mouse from a chronic study.
    Figure 2 of 2
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    comment:

    Hyperplasia of the mucosa is characterized by proliferation of squamous epithelium in the form of papillary folds (arrow, Figure 1image opens in a pop-up window ). It is an uncommon incidental finding and is unlikely to be associated with chemical administration.

    recommendation:

    This lesion should be diagnosed and given a severity grade.

    references: