Reproductive System, Male

Preputial Gland - Hyperplasia

    Narrative
    Preputial Gland, Epithelium - Hyperplasia. Hyperplasia in the preputial gland in a male F344/N rat from a chronic study.
    Preputial Gland, Epithelium - Hyperplasia. Higher magnification of Figure 1. Asterisks indicate eosinophilic granular material in the cytoplasm of hyperplastic glands in a male F344/N rat from a chronic study.
    Preputial Gland, Duct - Hyperplasia. Arrows indicate hyperplastic squamous epithelium with an anastomosing trabecular pattern in a male F344/N rat from a chronic study.
    Preputial Gland, Duct - Hyperplasia. Higher magnification of Figure 3 showing the interface between hyperplastic epithelium and adjacent cellular and necrotic debris within the duct lumen in a male F344/N rat from a chronic study.

    Authors

    Dianne M. Creasy, PhD, Dip RCPath, FRCPath
    Dianne Creasy Consulting LLC
    Pipersville, PA

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Gordon Flake, MD
    Staff Scientist
    NTP Pathologist
    Cellular and Molecular Pathology Branch
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Dipak K. Giri, DVM, PHD, DACVP
    Toxicologic Pathologist
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC

    Reviewers

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    David E. Malarkey DVM, PhD, DACVP, FIATP
    Head, National Toxicology Program Pathology Group
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC