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    Image of mineralization in the brain from a female F344/N rat in a subchronic study
    Incidental thalamic mineralization in a female F344/N rat from a 16-week study. The arrows identify focal mineral deposits.
    Image of mineralization in the brain from a male B6C3F1 mouse in a chronic study
    Incidental thalamic mineralization in a male B6C3F1 mouse from a chronic study. Note the irregular shape of the deposits at this high-magnification image.
    Image of mineralization in the brain from a male F344/N rat in a subchronic study
    A focus of mineral deposition in a site of former cerebellar neuronal necrosis (arrow) in a control male F344/N rat from a subchronic study.
    Image of mineralization in the brain from a male F344/N rat in a subchronic study
    Higher magnification of a focus of mineralization (calcospherites) at a site of former cerebellar internal granule cell necrosis (arrow) in a male F344/N rat from a subchronic study. Note the concentric lamellar nature of the concretions.
    Image of mineralization in the brain from a male F344/N rat
    Brain necrosis with ossification in a male F344/N rat from a chronic study. Note the osteoid (arrow) and osseous metaplasia (arrowhead) in a zone of former brain necrosis.