Special Senses System

Eye - Phthisis Bulbi

    Narrative
    Eye - Phthisis bulbi in a female B6C3F1 mouse from a chronic study. Phthisis bulbi ("end-stage" eye) is characterized by prominent shrinkage of the globe with marked structural displacement and disorganization
    Eye - Phthisis bulbi in a female B6C3F1 mouse from a chronic study. The globe is shrunken with marked structural displacement and disorganization.
    Eye - Phthisis bulbi in a female B6C3F1 mouse from a chronic study. There is marked shrinkage of the globe (arrow) with marked structural displacement and disorganization.
    Eye - Phthisis bulbi in a female B6C3F1 mouse from a lifetime study. The globe is shrunken (arrow) with marked structural displacement and disorganization and compressed by a large Harderian gland carcinoma (H).

    Author

    Margarita M. Gruebbel, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Ruth E. Hurley, DVM, PHD, DACVP
    Senior Veterinary Pathologist
    Huntingdon Life Sciences
    North Brunswick, NJ

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC