Eye, Retrobulbar - Hemorrhage

Eye, Retrobulbar - Hemorrhage in a male F344/N rat from a chronic study. There is hemorrhage (arrow) of the retrobulbar region; retrobulbar (R) and ocular (O) inflammation is also present.
Figure 1 of 2
comment:
Hemorrhage of the retrobulbar region ( Figure 1

recommendation:
Retrobulbar hemorrhage should be diagnosed and assigned a severity grade. If it is secondary to another pathologic process (e.g., intraorbital neoplasia), it should not be diagnosed separately, but should be described in the pathology narrative.references:
National Toxicology Program. 1993. NTP TR-394. Toxicology and Carcinogenesis Studies of Acetaminophen (CAS No. 103-90-2) in F344 Rats and B6C3F1 Mice (Feed Studies). NTP, Research Triangle Park, NC. Abstract: https://ntp.niehs.nih.gov/go/12239
Van Herck H, Baumans V, Van Der Craats NR, Hesp APM, Meijer GW, Van Tintelen G, Walvoort HC, Beynen AC. 1992. Histological changes in the orbital region of rats after orbital puncture. Lab Anim 6:53-58. Abstract: http://lan.sagepub.com/content/26/1/53.short
Web page last updated on: October 24, 2014