Kidney, Papilla, Epithelium - Hyperplasia

Kidney, Papilla, Epithelium - Hyperplasia in a male F344/N rat from a chronic study. The epithelium is thickened (arrows), and there are large clear spaces within the hyperplastic epithelium.
Figure 1 of 2
comment:
Hyperplasia of the surface epithelium of the renal papilla can range from thickening of the epithelium ( Figure 1

recommendation:
Hyperplasia of the renal papillary epithelium should be diagnosed and given a severity grade whenever present.related links:
Kidney, Urothelium - Hyperplasiareferences:
Frazier KS, Seely JC, Hard GC, Betton G, Burnett R, Nakatsuji S, Nishikawa A, Durchfeld-Meyer B, Bube A. 2012. Proliferative and non-proliferative lesions in the rat and mouse urinary system. Toxicol Pathol 40:14S-86S. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22637735
McInnes EF. 2012. Wistar and Sprague-Dawley rats. In: Background Lesions in Laboratory Animals: A Color Atlas. Saunders Elsevier, Edinburg, 29. Abstract: http://www.sciencedirect.com/science/book/9780702035197
Web page last updated on: October 28, 2014