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    Image of pigment in the spleen from a male F344/N rat in a chronic study
    Spleen - Pigment in a male F344/N rat from a chronic study. Multifocal macrophages with intracytoplasmic dark-brown granular pigment (arrow) are present within the splenic red pulp.
    Image of pigment in the spleen from a female Harlan Sprague-Dawley rat in a chronic study
    Spleen - Pigment in a female Sprague-Dawley rat from a chronic study. Macrophages with intracytoplasmic golden-brown pigment (arrow) are focally present within the splenic white pulp.